DMSO is a naturally occurring substance that has a wide range of distinctive properties which have immense therapeutic potential. In flip, 1000’s of research present DMSO safely1 treats a variety of:
• Accidents equivalent to sprains, concussions, burns, surgical incisions, and spinal wire trauma.
• Strokes, paralysis, many neurological issues (e.g., Down syndrome and dementia), and quite a few circulatory issues (e.g., Raynaud’s, varicose veins, or hemorrhoids).
• Power ache (e.g., from a foul disc, bursitis, arthritis, or advanced regional ache syndrome).
• Many autoimmune, protein, and contractile issues equivalent to scleroderma, amyloidosis, and interstitial cystitis.
• Head situations together with tinnitus, imaginative and prescient loss, dental issues, and sinusitis.
• Inside organ ailments equivalent to pancreatitis, infertility, liver cirrhosis, and endometriosis.
• Many pores and skin situations together with burns, varicose veins, zits, hair loss, ulcers, pores and skin most cancers, and lots of autoimmune dermatologic ailments.
• Difficult infections equivalent to shingles, herpes, continual ear or dental infections, and osteomyelitis.
Sadly, as soon as the FDA realized the extent to which DMSO would remodel medication, the company made the choice to erase it from historical past. In consequence, hundreds of thousands of sufferers whom it helped and the 1000’s of research on its therapeutic potential have been largely forgotten. Take into account for instance, this 1980 60 Minutes program:
Within the Sixties a miraculous remedy for continual ache, traumatic harm, strokes and spinal wire paralysis was found that unfold throughout America like wildfire—till the FDA buried it.
Right here, 60 Minutes uncovered the FDA utilizing the identical playbook they used all through COVID-19. A🧵 pic.twitter.com/Bh0dcjNk5w
— A Midwestern Physician (@MidwesternDoc) October 14, 2024
Happily, as a result of DMSO is efficient for a variety of situations, it is caught on like wildfire during the last six months (e.g., I’ve already obtained over 2,000 studies of outstanding responses to DMSO, many for a wide range of “incurable” situations).
DMSO and Most cancers
Because of the controversy round DMSO, its pioneers selected to downplay its anticancer potential to keep away from backlash in opposition to “unproven” therapies. In consequence, its cancer-fighting properties stay largely unknown. For instance, earlier on this collection, I introduced a whole lot of research that present DMSO:
• Successfully treats most cancers ache (which is commonly very difficult to deal with).
• Dramatically reduces most of the problems skilled from radiation remedy and chemotherapy.
• Stops cancers from rising and transforms cancerous cells again into regular cells.
• Considerably will increase the efficiency of anticancer brokers, making it attainable to make use of a lot decrease (and thus safer) doses of them whereas concurrently having a better remedy success price.
A number of the most outstanding advantages are seen when DMSO is mixed with unhazardous pure most cancers therapies (e.g., lately I reviewed the outstanding outcomes obtained from infusing DMSO blended with baking soda). Sadly, since there are virtually an limitless variety of mixtures, most haven’t been examined, and lots of unbelievable ones are probably ready to be found.
Word: DMSO mixtures can be utilized topically as DMSO transports substances contained in the physique and deep into most cancers cells.
Hematoxylin
Hematoxylin is a powder obtained from the logwood tree, which has been used for hundreds of years as each a dye and a medicinal substance.2 After being adopted by the textile trade, its oxidized kind (hematein), in 1830, was found to be glorious for staining many parts of cells together with DNA.3 It has remained one of many major stains utilized in pathology ever since (it is the “H” in H & E stains).
Whereas we presently use a systematized course of to develop medication (primarily based on their molecular targets), up to now, it was a way more haphazard course of that usually arose from incorrect assumptions.
For instance, the primary antibiotic was developed by mixing a substance identified to be poisonous to micro organism (arsenic)4 with a dye that stained bacterial cell partitions underneath the idea that the dye would enable arsenic to selectively goal micro organism.5
After many years of failed makes an attempt have been made to duplicate this method, one other “antimicrobial” dye was discovered,6 however earlier than lengthy it was found that the antimicrobial agent was not the dye itself however quite a colorless metabolic product of it, sulfanilamide.7
Equally, one of the outstanding therapies I do know of (Ultraviolet Blood Irradiation) was initially developed underneath the assumption that exposing the whole circulation to UV gentle would sterilize the bloodstream and therefore deal with a deadly an infection.
This didn’t work (it killed the take a look at canine) however earlier than lengthy, the inventor by accident solely irradiated a small fraction of the canine’s blood and received a outstanding outcomes as inputting a small quantity of UV gentle into the circulation transforms human physiology and permits the self-healing capability of the physique to deal with a variety of sicknesses (e.g., UVBI is a extremely efficient remedy for bacterial and viral infections, circulatory issues and autoimmune ailments).
Hematoxylin likewise follows an identical journey. Eli Jordon Tucker, Jr., M.D. was a extremely embellished orthopedic surgeon in Texas who made many vital orthopedic discoveries by means of bone analysis he did in his spare time. This required him to buy cattle bones from a meat packing firm, the place he noticed that many business cows had massive cancers overlaying their faces.
Questioning if there was a sort of cancer-resisting antibody in these cows, Tucker started administering extracts of their blood to lab rats and mice with cancers and noticed anticancer exercise for sure kinds of most cancers.
Because it was unclear how a lot of a change was occurring, Tucker appeared for a dye that would stain the tumors, and ultimately realized that hematoxylin was the right dye as a result of it stained the cancers one shade and regular cells one other. Sadly, hematoxylin had poor solubility (limiting his potential to experiment), so as soon as DMSO (a potent solvent) got here into use round 1963, Tucker began utilizing it.
He shortly found it may dissolve a really excessive focus of hematoxylin and that this combination selectively stained cancers leaving regular cells unaffected. Most significantly, there was a “marked improve in central necrosis of the neoplasm,” indicating this combination may probably remove cancers whereas sparing regular cells.8
Tucker then determined to conduct toxicity research (initially in canine) the place he discovered excessive concentrations of IV DMSO blended with hematoxylin (D-hematoxylin) had no toxicity to any of the tissues or organs he examined (and didn’t accumulate in any non-cancerous tissue). Curiously, the combination he made was 4 occasions much less poisonous than IV DMSO alone (which was already extraordinarily secure).
He then started treating spontaneous cancers in animals (e.g., in horses, canine and cows), which included terminal instances with large tumors (e.g., a large-cell lymphosarcoma, a small-cell lymphosarcoma, generalized malignant melanoma, a squamous cell carcinoma) together with an osteogenic sarcoma. In all of those instances, there was a immediate response, and the animal subsequently recovered.
Tucker’s Work
Tucker step by step decided a workable dose for D-hematoxylin and earlier than lengthy was approached by a colleague who had a comatose feminine affected person on the verge of dying from inoperable fibrosarcoma. D-hematoxylin prompted her tumor to recede till it could possibly be surgically eliminated (at which level she had a full restoration).
Inspired, Tucker handled extra sufferers. Finally, in 1968,9 he revealed outcomes from 37 most cancers sufferers: these receiving D-hematoxylin with different therapies noticed a 70% enchancment price, in comparison with simply 5% on typical therapies alone. Youthful, much less closely handled sufferers did finest, and topical or IV routes proved simplest.
Tucker’s sufferers included many dramatic recoveries — like a 3-year-old boy with terminal most cancers who lived into his 30s, a lady with aggressive lymphosarcoma cured after a 12 months of infusions and a high-level Exxon govt with superior colon most cancers survived and later accompanied Tucker to the FDA (who regardless of being astonished by Tucker’s instances nonetheless stonewalled D-hematoxylin).
Regardless of promising outcomes and minimal unintended effects the American Most cancers Society focused the remedy10 and Tucker shortly confronted a heavy backlash and was expelled from his hospital. Justifiably fearing he’d lose his license, he stopped publishing however continued privately treating determined sufferers (usually without spending a dime).
D-hematoxylin pale from view, with only some medical doctors utilizing it quietly over time. However the tales stay: of lives saved, cancers reversed, and a devoted physician who risked every little thing to supply hope when nobody else would.
Word: Andrew Ivy (who was arguably essentially the most influential physician in America on the finish of World Battle 2),11 like Tucker theorized there should be an element within the blood which resisted most cancers, and ultimately got here throughout a isolate (from cows injected with a cancer-causing fungus who’d then recovered) which did simply that.
After refusing to promote out to the AMA (who incessantly tried to purchase out competing therapies), he was blacklisted by each the FDA and AMA, and regardless of having 1000’s of compelling and well-documented instances exhibiting it cured most cancers, successfully had his total popularity destroyed as a result of he’d promoted an “unproven most cancers remedy.”
Hematoxylin Persists
After its preliminary discovery, DMSO shortly unfold throughout America, attracting many devoted proponents. As soon as the FDA tried to close down the usage of DMSO, a few of its proponents fought for many years to stop it from being forgotten.
Just a few of these (e.g., equivalent to maverick doctor William Campbell Douglass) likewise took up D-hematoxylin, and one medical journalist, podiatrist Morton Walker labored with Tucker in order that his method could possibly be preserved in print and proceed to assist sufferers into the long run.12
Certainly one of them, Jim McCann (a maverick Canadian engineer and self-taught healer), beginning with a high-dose remedy that saved a person dying of prostate most cancers, started experimenting with D-hematoxylin. He ultimately needed to relocate to Ecuador, the place he quietly skilled round 20 medical doctors. Over time, D-hematoxylin grew to become a fixture in Ecuador’s various medication scene, utilized by as many as 100 medical doctors.
Years later, an Ecuadorian physician efficiently used DMSO and antibiotics to deal with continual bacterial prostatitis, curing 44 of 45 sufferers. Impressed by McCann, he started utilizing an identical method for prostate most cancers, mixing hematoxylin with DMSO. The outcomes have been so promising, they sparked a 15-year examine that continues immediately.
Word: Each Tucker and the Ecuador workforce discovered D-hematoxylin has a really low LD50 (1257.16 mg/kg), which is between 10 to 100 occasions much less poisonous than many generally used most cancers medication.13 Likewise, hematoxylin alone has negligible toxicity.14 As such, aside from fevers or chills (which happen when too excessive of a dose is infused too shortly), no important unintended effects (e.g., indicators of organ harm) have been noticed from D-hematoxylin.
Latest D-Hematoxylin Sufferers
That mission concerned treating roughly 85 sufferers, with the remedy price in sufferers who had not beforehand obtained chemotherapy averaging between 80% to 90%. As such, D-hematoxylin is a superb most cancers remedy, however it’s not excellent and won’t work for everybody.
The cancers to this point discovered to have an excellent response to D-hematoxylin (a few of that are in any other case extraordinarily tough to deal with) included:
• Leukemias (significantly acute leukemias)
• Bile duct most cancers
• Sarcomas (together with delicate tissue sarcomas and osteosarcoma)
• Leiomyosarcoma
• Non-Hodgkin lymphoma
• Ovarian carcinoma
• Mediastinal tumors
• Bladder most cancers
• Cancers with an enormous cell tumor phenotype
Moreover, if a most cancers marker is related to the tumor (e.g., CEA15 or PSA)16 it’s going to usually drop quickly, making it straightforward to trace the progress of D-hematoxylin.
Word: There may be an preliminary improve within the tumor marker (because of the most cancers breaking down and releasing its parts to the bloodstream), however this shortly goes down.
As the next instances present, most of the enhancements have been fairly profound:
• A 54-year-old lady with Hodgkin’s Lymphoma (72% bone marrow involvement, CD20-positive) absolutely recovered utilizing solely D-hematoxylin and EDTA. Bone marrow biopsy confirmed most cancers selectively destroyed whereas wholesome cells regrew, with no recurrence after 12 years.
• A 72-year-old leukemia affected person noticed fast anemia enchancment with D-hematoxylin.
Likewise, comparable bone marrow adjustments have been seen in her:
• A 16-year-old male with mediastinal seminoma obtained D-hematoxylin, IV vitamin C, after which chemotherapy (cisplatin + bleomycin with DMSO). He absolutely recovered.
• A 63-year-old man with cholangiocarcinoma (a uncommon bile duct most cancers) handled with D-hematoxylin, chelation, and vitamin C however no chemotherapy. Tumor markers improved. Moreover, the most cancers particles could possibly be seen within the drainage tube (an internal-external percutaneous transhepatic biliary drainage catheter).
Likewise, one other bile duct most cancers affected person had a dramatic enchancment in her tumor markers following D-hematoxylin:
• A 63-year-old man with B-cell lymphoproliferative dysfunction obtained solely 10 days of D-hematoxylin solely and his WBC depend normalized.
• A person who had a steady bladder polyp which grew to become cancerous following a covid vaccination and when examined had unfold in a big portion of the urinary tract’s endothelium. It was surgically eliminated, however because of how far it had unfold, the urologist advised the affected person he would solely survive for 2 months. He then started 5 weeks of intravesical and IV D-hematoxylin and the most cancers by no means returned.
• A 55-year-old feminine who had a mediastinal tumor (sort unknown because it was wrapped 560° across the aorta and therefore couldn’t be biopsied) which absolutely resolved after 33 each day D-hematoxylin therapies.
Word: Her outstanding CT adjustments may be considered right here.
• A 27-year-old feminine with acute lymphoblastic leukemia reacted poorly to 2 classes of chemo, was categorized as terminal, after which was began on D-hematoxylin. She had a big enchancment in her most cancers and a simultaneous enchancment in her anemia which continued lengthy after typical therapies for anemia have been halted (which didn’t embody blood transfusions as she was a Jehovah’s Witness).
Moreover, video footage exhibits previous to her remedy she was very frail and had problem strolling, whereas after 31 days of remedy, she had no problem strolling and appeared vibrant and sturdy.
Word: 4 years later, she had a wholesome being pregnant (regardless of native hematologists having erroneously forecasted she would have points together with changing into severely anemic).
Moreover these sufferers confirmed:
• D-hematoxylin was considerably more practical than DMSO alone.
• Some tumors disappear shortly; others change into avascular or fibrotic, halting development and changing into simpler to take away surgically.
• Like many different pure most cancers therapies, one of the best outcomes have been seen in people who had not beforehand obtained chemotherapy. Likewise, each affected person who accomplished their D-hematoxylin protocol and had not beforehand obtained chemotherapy haven’t had any recurrences. Nevertheless, if chemotherapy was given just a few weeks after D-hematoxylin had been began, remedy successes elevated.
• In any other case wholesome people who had the most cancers quickly seem had one of the best response to D-hematoxylin.
How Does D-Hematoxylin Work?
Whereas DMSO has many anticancer properties, they don’t seem to be ample to clarify the fast adjustments noticed. Nevertheless, just a few clues trace at why this mix works:
• First, one researcher who studied D-hematoxylin discovered that it selectively travels to tumors however not regular tissue.17
• Second, he discovered that it prompted a dose-dependent alternation of tumor cell morphology and eventual dying that primarily affected the middle of the tumor (which is uncommon as usually chemotherapy impacts the periphery of tumors first, and sure partly because of DMSO’s potential to penetrate the cytoplasmic barrier which usually protects tumor cells).
Moreover, these adjustments continued after D-hematoxylin was stopped, suggesting it initiates a degenerative course of in tumors.
Word: Oral D-hematoxylin, whereas much less potent, additionally displayed these anticancer properties.
• Third, he discovered mobile harm initially started within the nucleus, suggesting D-hematoxylin had an affinity for DNA (which hematein does18). Following this, the most cancers cells, in successive levels, started to interrupt down and digest themselves (autolysis19), after which white blood cells started to invade the tumors to remove them.
• Fourth, he discovered that D-hematoxylin appeared to first dissolve the extracellular matrix round most cancers cells first, probably ravenous them.
Protein Kinase CK2
Protein Kinase CK2,20 when dysregulated, has been implicated in a whole lot of ailments,21 together with viral infections equivalent to COVID-19, autoimmune ailments, and neurological situations. Of these, it is best identified for enjoying a key position in most cancers (e.g., its exercise is commonly elevated in varied cancers, which contributes to tumor development and poor prognosis).
Hematein in flip, has been proven to inhibit CK2 with a excessive diploma of selectivity22,23,24 by way of binding to a subunit that’s over expressed in lots of cancers,25,26,27 correlates with a poor prognosis,28,29 and when inhibited, causes most cancers cells to endure programmed cell dying.30,31
A number of research have proven that hematein has selective antitumor results and may set off programmed cell dying in cancers.32,33,34,35 Moreover, like D-hematoxylin, CK2 inhibitors have additionally been proven to extend the sensitivity of cancers to chemotherapy.36,37
Lastly, many of the cancers that are extremely inclined to D-hematoxylin are additionally extremely depending on CK2 (significantly blood cancers38,39 — which CK2 inhibitors have repeatedly demonstrated efficacy in opposition to40,41,42). Likewise, cells dropping their attachment to the extracellular matrix (which DMSO and hematoxylin have been proven above to dissolve) triggers a type of cell dying (anoikis43), which CK2 confers resistance to in most cancers cells.44
As such, it’s probably CK2 performs a pivotal position in D-hematoxylin’s anticancer properties and it’s believable that along with DMSO potentiating hematoxylin, hematoxylin can also be potentiating DMSO’s anticancer properties.
Word: The opposite potential mechanisms for D-hematoxylin’s anticancer properties we’ve recognized are mentioned right here.
Conclusion
Over the past century, many promising most cancers cures have been found however then forgotten because of the medical trade’s hostility in the direction of something that threatens the most cancers monopoly. Having appeared by means of many, D-hematoxylin particularly stands out for its excessive diploma of efficacy, which is immensely lucky, as not like a lot of these different forgotten therapies, by advantage of it being composed of two easy and broadly out there chemical substances, it’s nonetheless readily accessible.
As such, I’m immensely grateful to the entire individuals who, for the final fifty years, labored tirelessly to protect Dr. Tucker’s discovery and I imagine the MAHA motion would be the time when these Forgotten Sides of Medication will eventually be capable to emerge.
Writer’s Word: That is an abridged model of an extended article which works into extra element on the entire knowledge on D-hematoxylin, the present protocols for its use and easy methods to find one of many medical doctors presently offering D-hematoxylin. That article, together with tips for common DMSO use may be learn right here. Moreover, a companion article detailing DMSO’s anticancer properties and the opposite most cancers therapies it enhances may be learn right here.
A Word from Dr. Mercola Concerning the Writer
A Midwestern Physician (AMD) is a board-certified doctor from the Midwest and a longtime reader of Mercola.com. I respect AMD’s distinctive perception on a variety of subjects and am grateful to share it. I additionally respect AMD’s want to stay nameless since AMD continues to be on the entrance traces treating sufferers. To search out extra of AMD’s work, you’ll want to try The Forgotten Facet of Medication on Substack.
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